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2.1 Molecules to metabolism

IB Syllabus Statements

Understandings:

  • Molecular biology explains living processes in terms of the chemical substances involved.

  • Carbon atoms can form four covalent bonds allowing a diversity of stable compounds to exist.

  • Life is based on carbon compounds including carbohydrates, lipids, proteins and nucleic acids.

  • Metabolism is the web of all the enzyme-catalysed reactions in a cell or organism.

  • Anabolism is the synthesis of complex molecules from simpler molecules including the formation of macromolecules from monomers by condensation reactions.

  • Catabolism is the breakdown of complex molecules into simpler molecules including the hydrolysis of macromolecules into monomers.

Applications and skills:

  • Application: Urea as an example of a compound that is produced by living organisms but can also be artificially synthesized.

  • Skill: Drawing molecular diagrams of glucose, ribose, a saturated fatty acid and a generalized amino acid.

  • Skill: Identification of biochemicals such as sugars, lipids or amino acids from molecular diagrams.

Videos

Intro to Molecular Biology

Condensation and Hydrolysis

Chemical Elements

Metabolism Intro

Falsifying the Vital Force

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Topic 2.1 Molecules to metabolism SSaQ (Syllabus Statement as Questions)

  • Define molecular biology.

  • How many bonds are formed by each of the following types of atoms: carbon, nitrogen, oxygen, hydrogen

  • Name 4 major groups of carbon compounds that life is based from.

  • Outline what is meant by the term metabolism.

  • Compare the terms anabolism and catabolism.

  • Explain how the artificial synthesis of urea helped to falsify vitalism.

  • Draw the following molecular diagrams: glucose (ring form, alpha-D and beta-D), ribose (ring form/D-ribose), a saturated fatty acid, a generalized amino acid (include the R-group).

  • Explain how you would use visual cues to identify the following biochemicals: sugars (monosaccharides and disaccharides), lipids (tryglycerides, phospholipids, steroids), amino acids.

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