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7.2 Transcription and gene expression

IB Syllabus Statements

Understandings:

  • Transcription occurs in a 5’ to 3’ direction.

  • Nucleosomes help to regulate transcription in eukaryotes.

  • Eukaryotic cells modify mRNA after transcription.

  • Splicing of mRNA increases the number of different proteins an organism can produce.

  • Gene expression is regulated by proteins that bind to specific base sequences in DNA.

  • The environment of a cell and of an organism has an impact on gene expression.

Application and skills:

  • Application: The promoter as an example of non-coding DNA with a function.

  • Skill: Analysis of changes in the DNA methylation patterns.

Videos

Details of Transcription (Part 1)

Post-Transcriptional Modification

Promoters and Transcription

DNA Replication (HL Details)

Modification of RNA in eukaryotes

Inheritance of Acquired Characteristics

Methylation and Epigenetics

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Topic 7.2 Transcription and gene expression HookED SOLO Hexagons

Topic 7.2 Transcription and gene expression SSaQ (Syllabus Statement as Questions)

  • Explain the relationship between DNA and mRNA.

  • Explain the direction in which transcription happens and the role of RNA polymerase.

  • Explain how nucleosomes help to regulate transcription in eukaryotes.

  • Outline how eukaryotic cells modify their mRNA after transcription.

  • Explain how splicing of mRNA can increase the number of different proteins an organism can produce.

  • Explain how gene expression can be regulated by proteins that bind to specific base sequences in DNA.

  • Explain why we think that the environment of a cell and of an organism can have an impact on gene expression.

  • Outline the role of the promoter as an example of non-coding DNA with a specific function.

  • Explain the importance of DNA methylation patterns.

  • Discuss the relevance of the ‘nature vs. nurture’ debate with this particular section of the IB Biology syllabus.

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